Aziridine bisphenol ethers and related compounds and methods for their use
US9365510B2 · kind B2 · utility
15Cited by
18References
46Claims
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Key dates
| Filing date | Apr 16, 2013 |
| Grant date | Jun 14, 2016 |
| Priority date | — |
| Expiry date | Apr 16, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds having a structure of Formula I:or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R, R1, R2, R3, R4, M1, M2, X, L1, L2, J1, J2, a1, a2, b1 and b2 are as defined herein, and wherein at least one of M2 or L2 is a moiety comprising an aziridine, acrylamide or sulfonate functional group, are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.