Compounds for use in the treatment of parasitic diseases
US9365541B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Oct 30, 2013 |
| Grant date | Jun 14, 2016 |
| Priority date | — |
| Expiry date | Oct 30, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds useful for treating parasitic diseases, which are infectious diseases caused or transmitted by a parasite. Compounds of the invention are particularly active against the causative pathogens in malaria. Such compounds are selective inhibitors of parasitic histone deacetylase (PfHDAC) and suppress the growth of parasites, such as Plasmodium falciparum, at a lower concentration than the concentration required for the inhibition of the growth of mammalian cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.