19-NOR neuroactive steroids and methods of use thereof
US9365611B2 · kind B2 · utility
44Cited by
5References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 17, 2014 |
| Grant date | Jun 14, 2016 |
| Priority date | — |
| Expiry date | Apr 17, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J31/006
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, and status epilepticus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.