Patent · US Active

Compositions and methods related to inhibitors of JAK kinase

US9371265B2 · kind B2 · utility

0Cited by
1References
6Claims
0Family size

Inventors

Key dates

Filing dateMar 26, 2013
Grant dateJun 21, 2016
Priority date
Expiry dateMar 26, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/20
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Embodiments are directed to JAK kinase inhibiting prodrug compounds of Formula Ib, containing a promoiety that results in alcohol derivative of the parent compound upon removal and methods of using an effective amount of said prodrug compounds in the treatment of a JAK-mediated disease or disorder in a subject. Preferred promoieties include phosphate, phosphonate, phosphate salt, sulfate, or sulfate salt.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.