Compositions and methods related to inhibitors of JAK kinase
US9371265B2 · kind B2 · utility
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1References
6Claims
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Inventors
Key dates
| Filing date | Mar 26, 2013 |
| Grant date | Jun 21, 2016 |
| Priority date | — |
| Expiry date | Mar 26, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Embodiments are directed to JAK kinase inhibiting prodrug compounds of Formula Ib, containing a promoiety that results in alcohol derivative of the parent compound upon removal and methods of using an effective amount of said prodrug compounds in the treatment of a JAK-mediated disease or disorder in a subject. Preferred promoieties include phosphate, phosphonate, phosphate salt, sulfate, or sulfate salt.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.