Patent · US Active

Comprehensive FMR1 genotyping

US9371560B2 · kind B2 · utility

0Cited by

16References

25Claims

0Family size

Assignee

ASURAGEN, INC. · US

Inventors

Ashish Choudhary · Austin, US
Gary J. Latham · Austin, US
Sachin Sah · Austin, US

Key dates

Filing date	Jul 19, 2013
Grant date	Jun 21, 2016
Priority date	—
Expiry date	Jul 25, 2033

Classification

Technology area (CPC G)Physics
CPC primaryG16B20/20
WIPO fieldComputer technology
WIPO sectorElectrical engineering

Abstract

Disclosed herein are methods for the automated reconstruction of a genotype of a gene, fragment, or genomic region using exhaustive enumeration. The methods can be used to reconstruct the genotype of any GC-rich sequence, such as the CGG repeat region in the 5′ UTR of FMR1 or the CCG repeat region in the 5′ UTR of FMR2. Also disclosed is an apparatus for use in conducting automated genotype reconstruction, as well as methods of diagnosis and treatment using exhaustive enumeration methods to reconstruct and identify genotypes associated with a disease or disorder.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.