Halogenated compounds for cancer imaging and treatment and methods for their use
US9375496B2 · kind B2 · utility
14Cited by
18References
23Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Sep 9, 2014 |
| Grant date | Jun 28, 2016 |
| Priority date | — |
| Expiry date | Sep 9, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/05
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds having a structure of Formula I:or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R4, R5, X1, X2, X3 and X4 are as defined herein, and wherein the compound comprises at least one F, Cl, Br, I or 123I moiety, are provided. Uses of such compounds for imaging diagnostics in cancer and therapeutics methods for treatment of subjects in need thereof, including prostate cancer as well as methods and intermediates for preparing such compounds are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.