Cyclin based inhibitors of CDK2 and CDK4
US9376465B2 · kind B2 · utility
4Cited by
2References
1Claims
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Key dates
| Filing date | Sep 22, 2014 |
| Grant date | Jun 28, 2016 |
| Priority date | — |
| Expiry date | Sep 22, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Structural and functional analysis of peptide inhibitor binding to the cyclin D and cyclin A groove has been investigated and used to design peptides that provide the basis for structure-activity relationships, have improved binding and have potential for development as chemical biology probes, as potential diagnostics and as therapeutics in the treatment of proliferative diseases including cancer and inflammation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.