Methods of synthesis and/or purification of diaminophenothiazinium compounds
US9382220B2 · kind B2 · utility
3Cited by
4References
28Claims
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Key dates
| Filing date | May 9, 2013 |
| Grant date | Jul 5, 2016 |
| Priority date | — |
| Expiry date | May 9, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds (referred to herein as “diaminophenothiazinium compounds”) including Methylthioninium Chloride (MTC) (also known as Methylene Blue), the resulting (high purity) compounds, compositions comprising such compounds (e.g., tablets, capsules), and the use of such high purity compounds. The compounds are useful in inactivating pathogens, and methods of medical treatment, prophylaxis, and diagnosis of diseases including a tauopathy, related neurological and infectious diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.