Process for preparation of dronedarone by oxidation of a hydroxyl group
US9382223B2 · kind B2 · utility
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4Claims
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Assignee
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Key dates
| Filing date | Feb 14, 2013 |
| Grant date | Jul 5, 2016 |
| Priority date | — |
| Expiry date | Feb 14, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/81
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a novel process for the preparation of dronedarone (I) and pharmaceutically acceptable salts thereof (formula I), which comprises oxidizing a compound of formula (VI), or a salt thereof and the obtained product is isolated and, if desired, converted into a pharmaceutically acceptable salt thereof. Further aspects of the invention include the novel intermediary compound of formula (VI) and process for the preparation thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.