Cyclic depsipeptide compounds and their uses
US9382295B2 · kind B2 · utility
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20Claims
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Assignee
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Key dates
| Filing date | Oct 2, 2013 |
| Grant date | Jul 5, 2016 |
| Priority date | — |
| Expiry date | Oct 2, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel cycloundecadepsipeptide compounds and their analoges which bind and inhibit cyclophilins, have reduced immunosuppressive activity and improved physicochemical properties including water solubility. The present invention further relates to pharmaceutical compositions containing said depsipeptide compounds and their analoges for use in the treatment or prevention of diseases and pathologies which may be ameliorated by the inhibition of cyclophilin activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.