Octapeptide compounds derived from somatostatin and the therapeutic use thereof
US9382306B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 29, 2009 |
| Grant date | Jul 5, 2016 |
| Priority date | — |
| Expiry date | Oct 10, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel octapeptide compounds of general formula (I): H-2-Nal 1-cyclo(Cys2-Tyr3-AA4-Lys5-Val6-Cys7)-Thr8-NH2. Since these products have a good affinity for certain somatostatin receptor subtypes, they are particularly advantageous for treating pathological states or diseases in which one (or more) somatostatin receptor(s) is (are) involved. These compounds furthermore have physiochemical properties that make it possible to envisage them in diverse solutions for the formulation of medicaments, for example as a pharmaceutically acceptable carrier. The invention also relates to pharmaceutical compositions containing said products and to the use thereof for the preparation of a medicament.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.