Variant activin IIB receptor
US9382309B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Mar 11, 2014 |
| Grant date | Jul 5, 2016 |
| Priority date | — |
| Expiry date | Mar 11, 2034 |
Classification
- Technology area (CPC —)General
Abstract
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.