Pdia4, target of cytopiloyne derivatives, for tumor diagnosis and treatment
US9382330B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | May 9, 2011 |
| Grant date | Jul 5, 2016 |
| Priority date | — |
| Expiry date | Jan 15, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/99
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of diagnosing cancer that are based in part on the findings that Pdia4 promotes cell growth, cell proliferation, and cell cycle are disclosed herein. Methods of using microvessel density as a surrogate marker and reducing tumor microvessel density in a subject are also enclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.