Derivatives of dillapiol and related monolignans and use thereof
US9386767B2 · kind B2 · utility
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Key dates
| Filing date | May 11, 2012 |
| Grant date | Jul 12, 2016 |
| Priority date | — |
| Expiry date | Feb 23, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/68
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Derivatives of dillapiol, sesamol and related monolignans having the following general formula:These compounds have synergistic properties, inhibit cytochrome P450 enzymes such as human CYP3A4, and can be used as pesticide synergists or pharmaco-enhancers. Accordingly, methods for increasing the efficacy and/or bioavailability of a pharmaceutically active agent and for increasing the potency of a pesticide are described, as are synergistic pesticidal and pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.