Agent for evading immune response
US9387175B2 · kind B2 · utility
2Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 3, 2012 |
| Grant date | Jul 12, 2016 |
| Priority date | — |
| Expiry date | Dec 23, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC01P2006/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
It has been found that modification of surfaces of nanoparticles with a RolA protein decreases an immunostimulation activity of the nanoparticles on myeloid dendritic cells and also decreases phagocytosis of the nanoparticles by macrophages. The present invention provides nanoparticles being modified with a biological molecule and having an immune-response evasion function.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.