Patent · US Active

Neprilysin inhibitors

US9388145B2 · kind B2 · utility

8Cited by
34References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 16, 2015
Grant dateJul 12, 2016
Priority date
Expiry dateJul 16, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D498/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In one aspect, the invention relates to compounds having the formula:where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.