Patent · US Active

Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis

US9388147B2 · kind B2 · utility

2Cited by
14References
36Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 26, 2015
Grant dateJul 12, 2016
Priority date
Expiry dateFeb 26, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.