Methods for producing 5-(halomethyl) furfural

US9388151B2 · kind B2 · utility

Assignee

• MICROMIDAS, INC. · US

Inventors

• Shawn M. Browning · Sacramento, US
• John Bissell · Sacramento, US
• Ryan L. Smith · Sacramento, US
• Makoto N. Masuno · Elk Grove, US
• Benjamin Nicholson · Sacramento, US
• Alex B. Wood · Sacramento, US

Key dates

• Filing date: Oct 25, 2013
• Grant date: Jul 12, 2016
• Expiry date: Oct 25, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D307/50
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure provides methods to produce 5-(halomethyl)furfural, including 5-(chloromethyl)furfural, by acid-catalyzed conversion of biomass. The methods make use of certain organic solvents with temperature-dependent solubility for 5-(halomethyl)furfural. This allows for temperature-dependent phase separation of the 5-(halomethyl)furfural from the reaction mixture. In certain embodiments, solid 5-(halomethyl)furfural may be obtained. The solid 5-(halomethyl)furfural obtained may be amorphous or crystalline.