Substituted diazaspiroalkanes as androgen receptor modulators

US9388159B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Michael E. Jung · Los Angeles, US
• Charles L. Sawyers · New York, US
• Samedy Ouk · San Diego, US
• Chris Tran · New York, US
• John Wongvipat · Nanuet, US

Key dates

• Filing date: Jun 27, 2014
• Grant date: Jul 12, 2016
• Expiry date: Jun 27, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides for compounds of the Formula II:wherein A, B, Het, R1, R2 and R3 are as described herein. These compounds are androgen receptor modulators useful for the treatment of androgen receptor-associated conditions.