Patent · US Active

PRMT5 inhibitors and uses thereof

US9388173B2 · kind B2 · utility

32Cited by
29References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 15, 2014
Grant dateJul 12, 2016
Priority date
Expiry dateOct 15, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.