Inhibitor compounds of phosphodiesterase type 10A

US9388180B2 · kind B2 · utility

Assignees

• Abb Vie Inc. · US
• Abbott GmbH & Co. KG · DE

Inventors

• Hervé Geneste · Schifferstadt, DE
• Michael Ochse · Wiesbaden, DE
• Karla Drescher · Ludwigshafen, DE
• Clarissa Jakob · North Chicago, US
• Maricel Torrent · Lake Bluff, US

Key dates

• Filing date: Sep 17, 2013
• Grant date: Jul 12, 2016
• Expiry date: Jun 18, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof. The compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof are inhibitors of phosphodiesterase type 10A and to their use for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.