Protein disulfide isomerase assay method for the in vitro diagnosis of colorectal cancer
US9388404B2 · kind B2 · utility
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Key dates
| Filing date | Jan 2, 2013 |
| Grant date | Jul 12, 2016 |
| Priority date | — |
| Expiry date | Jan 2, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/99
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for the in vitro diagnosis of colorectal cancer that comprises determining the presence of the protein disulfide isomerase tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-PDI monoclonal antibody directed against a PDI epitope chosen from the epitopes of sequence SEQ ID No.1, SEQ ID No.2, with an aromatic amino acid which is close in the three-dimensional structure of PDI and SEQ ID No.3.
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