Methods for screening inhibitors of tumor associated protein aggregation
US9389219B2 · kind B2 · utility
2Cited by
0References
15Claims
0Family size
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Key dates
| Filing date | Mar 26, 2012 |
| Grant date | Jul 12, 2016 |
| Priority date | — |
| Expiry date | Mar 26, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The disclosure relates to the fields of protein aggregation diseases including cancer. More specifically, it concerns a screening method for identifying compounds that inhibit or disrupt co-aggregation of one or more member proteins of a disease-related protein aggregome, in particular, a tumor-associated protein aggregome. Further, disclosed are agents and compounds identified by the screening method that can be applied to prevent or to treat protein aggregation diseases, such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.