PKM2 modulators and methods for their use
US9394257B2 · kind B2 · utility
19Cited by
1References
52Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 16, 2013 |
| Grant date | Jul 19, 2016 |
| Priority date | — |
| Expiry date | Oct 16, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65031
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.