Substituted phenylimidazopyrazoles and their use

US9394309B2 · kind B2 · utility

Assignees

• Bayer Pharma Aktiengesellschaft · DE
• Bayer Intellectual Property GmbH · DE

Inventors

• Frank Süβmeier · Birkenfeld, DE
• Mario Lobell · Wuppertal, DE
• Sylvia Grünewald · Berlin, DE
• Michael Härter · Wixom, US
• Bernd Buchmann · Hohen Neuendorf, DE
• Joachim Telser · Wuppertal, DE
• Hannah Jörißen · Heiligenhaus, DE
• Melanie HEROULT · Mülheim an der Ruhr, DE
• Antje Kahnert · Wuppertal, DE
• Klemens Lustig · Wuppertal, DE
• Niels Lindner · Wuppertal, DE

Key dates

• Filing date: Jan 23, 2013
• Grant date: Jul 19, 2016
• Expiry date: Feb 2, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel 1-phenyl-1H-imidazo[1,2-b]pyrazole derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular angiogenic disorders and hyperproliferative disorders, where neovascularization plays a role, such as, for example, neoplastic disorders and tumor disorders. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.