Patent · US Active

Transfer hydrogenation of cyclopamine analogs

US9394313B2 · kind B2 · utility

12Cited by

44References

24Claims

0Family size

Assignee

Infinity Pharmaceuticals, Inc. · US

Inventors

Daniel Genov · Boston, US
Brian C. Austad · Tewksbury, US
Brian H. White · Malden, US

Key dates

Filing date	Sep 14, 2011
Grant date	Jul 19, 2016
Priority date	—
Expiry date	Dec 1, 2032

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01J2531/821
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided herein is a process for the transfer-hydrogenation of ketone analogs of members of the jervine type of Veratrum alkaloids, such as cyclopamine. Also provided herein are novel ruthenium transfer-hydrogenation catalysts.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.