Nucleoside crystals, crystal nucleation and growth control with antifreeze proteins
US9394327B1 · kind B1 · utility
2Cited by
12References
11Claims
0Family size
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Key dates
| Filing date | Mar 15, 2013 |
| Grant date | Jul 19, 2016 |
| Priority date | — |
| Expiry date | Nov 15, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/483
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The uses of antifreeze proteins (AFPs), including polypeptides, peptides, fragments of AFPs, and mimicries of AFPs, as highly efficient additives for crystal growth control are provided. AFPs are demonstrated to efficiently inhibit the nucleation of commercially and pharmaceutically important compounds (e.g., nucleosides, sugars, salts), increase the supersaturation of their solutions, modify their crystal habits, and result in novel morphologies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.