Tough hydrogels

US9394384B2 · kind B2 · utility

Assignee

• The General Hospital Corporation · US

Inventors

• Orhun K. Muratoglu · Cambridge, US
• Jeeyoung Choi · Sunnyvale, US
• Hatice Bodugoz-Senturk · Boston, US
• Gavin Braithwaite · Cambridge, US
• Stephen H. Spiegelberg · Winchester, US

Key dates

• Filing date: Sep 27, 2005
• Grant date: Jul 19, 2016
• Expiry date: Apr 26, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08L71/02
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The invention provides fabricated tough hydrogels, hydrogel-containing compositions, and methods of making the same. The invention also provides methods of implanting or administering the tough hydrogels, or the hydrogel-containing compositions to treat a subject in need. Methods of cross-linking pre-solidified or pre-gelled hydrogel particles and making crosslinked tough hydrogels, and crosslinked tough hydrogel-containing compositions also are disclosed herein.