Self-renewal promoter for neural stem cells and method for using same
US9394516B2 · kind B2 · utility
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Key dates
| Filing date | Apr 26, 2011 |
| Grant date | Jul 19, 2016 |
| Priority date | — |
| Expiry date | Apr 26, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An object of the present invention to provide an agent for promoting the self-renewal of the neural stem cells and a method of using the same. ECF-L contained in a culture supernatant of endothelial progenitor cells derived from bone marrow has an effect of promoting the self-renewal of neural stem cells. Accordingly, ECF-L can be used as an ingredient of an agent for promoting the self-renewal of the neural stem cells, a pharmaceutical composition for growing the neural stem cells, and a pharmaceutical composition for treating a disease associated with neural dysfunction.
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