Electrode system for measuring an analyte concentration under in-vivo conditions

US9394563B2 · kind B2 · utility

Assignee

• Roche Diabetes Care, Inc. · US

Inventors

• Ortrud Quarder · Heidelberg, DE
• Arnulf Staib · Heppenheim, DE
• Reinhold Mischler · Ludwigshafen, DE
• Ewald Rieger · Frankenthal (Pfalz), DE
• Ralph Gillen · Papenburg, DE
• Ulrike Kamecke · Mannheim, DE

Key dates

• Filing date: Mar 8, 2011
• Grant date: Jul 19, 2016
• Expiry date: Apr 26, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B5/7207
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

An electrode system for measuring the concentration of an analyte under in-vivo conditions comprises a counter-electrode having an electrical conductor, a working electrode having an electrical conductor on which an enzyme layer containing immobilized enzyme molecules for catalytic conversion of the analyte is arranged, and a diffusion barrier that slows the diffusion of the analyte from body fluid surrounding the electrode system to enzyme molecules. The enzyme layer is in the form of multiple fields that are arranged on the conductor of the working electrode at a distance from each other.