Patent · US Active

Devices and methods for target molecule characterization

US9395352B2 · kind B2 · utility

22Cited by

17References

17Claims

0Family size

Assignee

ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · US

Inventors

Stuart Lindsay · Tempe, US
Peiming Zhang · Gilbert, US

Key dates

Filing date	Apr 7, 2008
Grant date	Jul 19, 2016
Priority date	—
Expiry date	Dec 18, 2030

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/48721
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention provides a device having at least one constriction that is sized to permit translocation of only a single copy of the molecule. The device has a pair of spaced apart sensing electrodes that border the constriction, which may be a nanopore. The first electrode is connected to a first affinity element and the second electrode is connected to a second affinity element. The first and second affinity elements are configured to temporarily form hydrogen bonds with first and second portions of the target molecule as the latter passes through the constriction.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.