Methods for detecting allosteric modulators of protein
US9395358B2 · kind B2 · utility
3Cited by
29References
21Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 25, 2013 |
| Grant date | Jul 19, 2016 |
| Priority date | — |
| Expiry date | Jul 30, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention discloses, inter alia, methods for labeling a target protein with an SHG-active probe for detection by second harmonic or sum-frequency generation in order to identify agents which bind to an allosteric site on the target protein thereby altering its structural conformation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.