Renal function analysis method and apparatus

US9398876B2 · kind B2 · utility

Assignee

• PHARMACOPHOTONICS, INC. · US

Inventors

• Exing Wang · Carmel, US
• Daniel Meier · Indianapolis, US
• Robert Bunch · Peoria, US
• Bruce A. Molitoris · Indianapolis, US
• Ruben Sandoval · Indianapolis, US
• Matthew Rubin · Cambridge, US

Key dates

• Filing date: Dec 13, 2012
• Grant date: Jul 26, 2016
• Expiry date: Jul 26, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.