Synthetic route to pactamycin and pactamycin analogs
US9399652B2 · kind B2 · utility
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Key dates
| Filing date | Jan 23, 2014 |
| Grant date | Jul 26, 2016 |
| Priority date | — |
| Expiry date | Jan 23, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Methods and intermediates useful for making compounds of Formula (I) are described, including a general method of making an alpha, beta-diamino ketone by reacting an imine with a 2-amino-substituted 1,3-dicarbonyl in a Mannich addition reaction to produce said alpha,beta-diamino ketone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.