Process for purification of pneumocandin

US9399664B2 · kind B2 · utility

Assignee

• Biocon Ltd. · IN

Inventors

• Kushal Rastogi · Nagamangala, IN
• Onkar Prakash Santan · Bengaluru, IN
• Nitin Sopanrao Patil · Savanuru, IN
• Rakesh Mendhe · Savanuru, IN

Key dates

• Filing date: May 17, 2010
• Grant date: Jul 26, 2016
• Expiry date: Dec 14, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K7/56
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The process described herein discloses purification process of a secondary metabolite produced by fermentation route. The process involves selective removal of impurities at various stages of washings, charcoalization followed by crystallization. The product is closely related to class of echinocandins and is found to be potent antifungal compound & a key ingredient in the synthesis of antifungal drugs.