7-hydroxycoumarin-based cell-tracking reagents
US9400273B1 · kind B1 · utility
34Cited by
7References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 16, 2015 |
| Grant date | Jul 26, 2016 |
| Priority date | — |
| Expiry date | Jul 16, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2430/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described herein are compounds, methods, and kits for long-term tracking of cell proliferation, differentiation, and/or function. The compounds of the present invention are novel cell-tracking reagents, efficiently excitable with a 405-nm violet laser, that provide bright fluorescence intensity, uniform cell staining, and good retention within cells as well as low toxicity toward cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.