Viral particles derived from an enveloped virus
US9402894B2 · kind B2 · utility
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7Claims
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Assignee
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Key dates
| Filing date | Oct 26, 2012 |
| Grant date | Aug 2, 2016 |
| Priority date | — |
| Expiry date | Oct 26, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to generating a vaccine based on immunogens from viral particles that initially have replication competency but are then inactivated by chemical, biophysical or other methods. The components of this vaccine may be a non-HIV enveloped virus that contains and expresses a gene related to the HIV Envelope gene such that the Envelope protein is expressed on the surface of viral particles. These viral particles may be further treated to reduce their replication competency. The vaccine further may contain components to improve its immunogenicity, tolerability, stability and ease of manufacture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.