Patent · US Active

Pharmaceutical dosage form comprising polymeric carrier composition

US9402909B2 · kind B2 · utility

0Cited by

1References

10Claims

0Family size

Assignee

Abb Vie Deutschland Gmbh & Co. KG · DE

Inventors

Bernd Liepold · Dossenheim, DE
Jorg Breitenbach · Mannheim, DE
Markus Mägerlein · Mannheim, DE
Claudia Henzel · Mannheim, DE
Thomas Kessler · Schifferstadt, DE

Key dates

Filing date	Jan 10, 2014
Grant date	Aug 2, 2016
Priority date	—
Expiry date	Feb 25, 2034

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A pharmaceutical dosage form comprises a solid dispersion product of at least one active ingredient dispersed in a polymeric binder composition, the polymeric carrier composition comprising a) a vinylpyrrolidone homopolymer, wherein at least 95% by weight of the vinylpyrrolidone homopolymer has a molecular weight distribution within the range of from 1000 to 13 000; and b) a vinylpyrrolidone copolymer having a weight-average molecular weight of from 5000 to 1 500 000. The dosage form is preferably prepared by a melt extrusion process. The polymeric carrier composition exhibits a high drug dissolution power and allows a reduction of the viscosity of the melt without deteriorating the mechanical properties and storage stability of the dosage form.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.