Pyridonemorphinan analogs and biological activity on opioid receptors
US9403824B2 · kind B2 · utility
8Cited by
29References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 28, 2015 |
| Grant date | Aug 2, 2016 |
| Priority date | — |
| Expiry date | Jan 28, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The application is directed to compounds of Formula I-Aand pharmaceutically acceptable salts and solvates thereof, wherein , R1a-R3a, R4, Y and Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I-A to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.