Compositions and methods for detection and treatment of cancer
US9403911B2 · kind B2 · utility
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6References
17Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 6, 2012 |
| Grant date | Aug 2, 2016 |
| Priority date | — |
| Expiry date | Jun 6, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2400/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Novel antibodies for the detection and/or treatment of a cancer (e.g., a pancreatic cancer or an ovarian cancer) are provided. In certain embodiments the antibodies bind a region of the MUC4 protein that does not comprise the central tandem repeat (TR) domain of MUC4. Certain antibodies bind to the MUC4 peptide fragment MUC4-α-N-Ter and/or to the MUC4 peptide fragment MUC4-α-C-Ter. Chimeric constructs comprising such antibodies are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.