Patent · US Active

Automatic isothermal titration microcalorimeter apparatus and method of use

US9404876B2 · kind B2 · utility

1Cited by
64References
39Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 11, 2015
Grant dateAug 2, 2016
Priority date
Expiry dateJun 11, 2035

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2035/0474
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Automated isothermal titration micro calorimetry (ITC) system comprising a micro calorimeter with a sample cell and a reference cell, the sample cell is accessible via a sample cell stem and the reference cell is accessible via a reference cell stem. The system further comprises an automatic pipette assembly comprising a syringe with a titration needle arranged to be inserted into the sample cell for supplying titrant, the pipette assembly comprises an activator for driving a plunger in the syringe, a pipette translation unit supporting the pipette assembly and being arranged to place pipette in position for titration, washing and filling operations, a wash station for the titrant needle, and a cell preparation unit arranged to perform operations for replacing the sample liquid in the sample cell when the pipette is placed in another position than the position for titration.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.