Measuring biological tissue parameters using diffusion magnetic resonance imaging
US9404986B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 7, 2012 |
| Grant date | Aug 2, 2016 |
| Priority date | — |
| Expiry date | Mar 23, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/48
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods, devices and systems are disclosed for measuring biological tissue parameters using restriction spectrum magnetic resonance imaging. In one aspect, a method of characterizing a biological structure includes determining individual diffusion signals from magnetic resonance imaging (MRI) data in a set of MRI images that include diffusion weighting conditions (e.g., diffusion gradient directions, diffusion gradient strengths, sensitivity factors (b-values), or diffusion times), combining the individual diffusion signals to determine a processed diffusion signal corresponding to at least one location within one or more voxels of the MRI data, calculating one or more parameters from the processed diffusion signal by using the diffusion weighting conditions, and using the one or more parameters to identify a characteristic of the biological structure, in which the one or more parameters include values over a range of one or more diffusion length scales based on at least one of diffusion distance or diffusion rate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.