Integrated analysis device for simultaneously detecting EBCs and VOCs in human exhaled breath

US9408556B2 · kind B2 · utility

Assignee

• ZHEJIANG UNIVERSITY · CN

Inventors

• Ping Wang · North Oaks, US
• Di Wang · Timonium, US
• Le Wang · Helsinki, FI
• Jin-Quan Yu · San Diego, US
• Kai-Hung Yu · Albany, US
• Yishan Wang · Taochang, CN
• Lin Wang · Cincinnati, US
• Cong Zhao · Nanhu, CN

Key dates

• Filing date: Dec 1, 2010
• Grant date: Aug 9, 2016
• Expiry date: Jun 8, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/497
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present embodiments disclose a device including a module for sampling, separating and enriching a detected object, an exhaled breath condensates (EBCs) detection module and a combined volatile organic compounds (VOCs) detection module. The sampling module is connected with the EBCs detection module via a syringe pump for sample injection and is connected with the combined VOCs detection module by a capillary separation column. EBCs and VOCs in human exhaled breath are simultaneously sampled, separated and condensed; the heavy metal ions, cell factors, etc. in the collected EBCs are detected with a light addressable potentiometric sensor (LAPS); the condensed VOCs can be quantitatively detected by the combined VOCs detection module with a high sensitivity; and a heating rod and a platinum resistor can be conveniently replaced because a separated outlet heating piece is designed in the combined VOCs detection module.