Immobilised biological entities

US9408950B2 · kind B2 · utility

Assignee

• W.L. Gore & Associates GmbH · DE

Inventors

• Karin Leontein · Upplands Väsby, SE
• Per Antoni · Upplands Väsby, SE
• Daniel Nyström · Upplands Väsby, SE
• Paul Begovac · Flagstaff, US
• Krzysztof Pietrzak · San Francisco, US

Key dates

• Filing date: Jul 2, 2015
• Grant date: Aug 9, 2016
• Expiry date: Jul 2, 2035

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/31971
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

There is described inter alia a device having a surface comprising a layered coating wherein the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular weight 14-1,000 Da (ii) a total molecular weight of 1,500 to 1,000,000 Da (iii) a ratio of total molecular weight to core moiety molecular weight of at least 80:1 and (iv) functional end groups, whereby one or more of said functional end groups have an anti-coagulant entity covalently attached thereto.