Method for treating amyloid disease

US9409146B2 · kind B2 · utility

Assignee

• NEW YORK UNIVERSITY · US

Inventors

• Blas Frangione · New York, US
• Einar M. Sigurdsson · Scarsdale, US
• Thomas Wisniewski · Staten Island, US
• Jorge Ghiso · Elmhurst, US

Key dates

• Filing date: Oct 18, 2012
• Grant date: Aug 9, 2016
• Expiry date: Oct 18, 2032

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01J2220/66
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are methods for treating amyloid disease in humans by clearing amyloid peptides from one or more bodily fluids such as, e.g., blood, of a patient. In particular, the methods are based on the administration of compounds capable of binding to amyloid-beta (Aβ) or on dialysis of blood or plasma exchange in order to remove Aβ peptides from the blood circulation, and/or brain or other affected organs.