Benzamide derivatives as modulators of the follicle stimulating hormone

US9409897B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Henry Yu · Wellesley, US
• Thomas E. Richardson · Durham, US
• Pandi Bharathi · Cary, US
• Brian H. Heasley · Wake Forest, US
• Matthew G. Jenks · Durham, US
• Robert James Foglesong · Durham, US

Key dates

• Filing date: Jan 9, 2013
• Grant date: Aug 9, 2016
• Expiry date: Jun 2, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel benzamide derivatives of formula (I)wherein W1, W2, R1 to R10 and X have the meaning according to the claims, are positive allosteric modulators of the FSH receptor, and can be employed, inter alia, for the treatment of fertility disorders.