Patent · US Active

Bis-met histones

US9409960B2 · kind B2 · utility

2Cited by

1References

19Claims

0Family size

Assignee

Symbiotec Gesellschaft zur Forschung und Entwicklung auf dem Gebiet der Biotechnologie mbH · DE

Inventors

Peter Gross · Bexbach, DE
Hans Jornvall · Mölndal, SE
Grazyna Formicka-Zeppezauer · Riegelsberg, DE
Michael Zeppezauer · Scheidt, DE
Michel Thiry · Trooz, BE

Key dates

Filing date	Apr 7, 2008
Grant date	Aug 9, 2016
Priority date	—
Expiry date	Oct 8, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/143333
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing said nucleic acid molecule, a host transformed with said vector, polypeptides encoded by the nucleic acid molecule and pharmaceutical and diagnostic compositions. The present invention also relates to the use of the nucleic acid molecule, vectors, hosts and the polypeptide of the invention for the preparation of a composition for the treatment of diseases. Furthermore, the present invention relates to a method of testing for the presence of the nucleic acid molecule or the polypeptide in a sample and to a kit.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.