Patent · US Active

Alkyne-activated fluorogenic azide compounds and methods of use thereof

US9410958B2 · kind B2 · utility

6Cited by

10References

36Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Carolyn R. Bertozzi · Berkeley, US
Peyton Shieh · Cambridge, US

Key dates

Filing date	Mar 23, 2015
Grant date	Aug 9, 2016
Priority date	—
Expiry date	Mar 23, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC09B69/008
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present disclosure provides fluorogenic azide compounds. Also provided are methods of using the subject compounds for labelling a target biomolecule that includes an alkyne. In some embodiments, the method includes contacting the biomolecule with a fluorogenic azide compound, wherein the contacting results in covalent linkage of the compound with the alkyne moiety of the target biomolecule.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.