Cellarium: thin-film sensor with microarray seal

US9410970B2 · kind B2 · utility

Assignee

• ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · US

Inventors

• Yanqing Tian · Tempe, US
• Liqiang Zhang · Shandong, CN
• Fengyu Su · Tempe, US
• Deirdre Meldrum · Phoenix, US
• Sean Buizer · Tempe, US
• Clifford L. Anderson · Tempe, US
• Laimonas Kelbauskas · Gilbert, US
• Kristen Lee · Mesa, US

Key dates

• Filing date: Nov 5, 2014
• Grant date: Aug 9, 2016
• Expiry date: Nov 5, 2034

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/66
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A triple sensor structured for simultaneous measurement of glucose, oxygen, and pH. The sensor components are in thin film states such as sensing films or membranes, with a glucose probe associated with emission of radiation in the blue part of the spectrum, an oxygen probe associated with radiation in red portion of the spectrum, and a pH probe—with a green portion of the spectrum. The optical probes are chemically grafted or immobilized in a suitable polymer matrix, alleviating the leaching of the probes from the matrix, improving the thin film sensing stability, and enabling the repeatable use of the same sensing films.