Methods and compositions for localized delivery of agents to virally infected cells and tissues
US9415070B2 · kind B2 · utility
2Cited by
1References
20Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Nov 8, 2013 |
| Grant date | Aug 16, 2016 |
| Priority date | — |
| Expiry date | Nov 8, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/127
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compositions and methods for delivering an agent to virally infected tissues and/or cells of a subject by conjugating agent-loaded nanoparticles to virus-specific T cells, such as cytotoxic T lymphocytes. The agent may be a latency-reversing drug (LRD), an antiviral agent and/or an agent that enhances cytotoxic efficacy of T lymphocytes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.